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Farukh A Durrani Selected Research

6- (3- (2- hydroxyethyl)amino- 1- propyl)- 5,6- dihydro- 2,3- dimethoxy- 8,9- methylenedioxy- 5,11- dioxo- 11H- indeno(1,2- )isoquinoline

2/2005Cellular topoisomerase I inhibition and antiproliferative activity by MJ-III-65 (NSC 706744), an indenoisoquinoline topoisomerase I poison.

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Farukh A Durrani Research Topics

Disease

29Neoplasms (Cancer)
12/2023 - 02/2004
7Squamous Cell Carcinoma of Head and Neck
12/2011 - 04/2004
5Hypoxia (Hypoxemia)
10/2018 - 12/2004
4Carcinoma (Carcinomatosis)
05/2007 - 04/2004
3Colorectal Neoplasms (Colorectal Cancer)
04/2012 - 04/2006
2Brain Neoplasms (Brain Tumor)
12/2023 - 12/2020
2Renal Cell Carcinoma (Grawitz Tumor)
10/2018 - 07/2012
2Colonic Neoplasms (Colon Cancer)
07/2012 - 07/2009
1Phototoxic Dermatitis (Phototoxicity)
12/2023
1Erectile Dysfunction
06/2023
1Prostatic Neoplasms (Prostate Cancer)
06/2023
1Lung Neoplasms (Lung Cancer)
04/2022
1Adenocarcinoma
04/2022
1Neoplasm Metastasis (Metastasis)
01/2022
1Urinary Bladder Neoplasms (Bladder Cancer)
01/2019
1Fever (Fevers)
01/2018
1Hyperthermia
01/2018
1Necrosis
06/2011
1Head and Neck Neoplasms (Head and Neck Cancer)
01/2010
1Diarrhea
02/2007
1Weight Loss (Weight Reduction)
02/2007
1Inflammation (Inflammations)
02/2007
1Poisoning
02/2005
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
12/2004

Drug/Important Bio-Agent (IBA)

16Irinotecan (Camptosar)FDA LinkGeneric
04/2012 - 02/2004
81-phenyl-3,3-dimethyltriazene (PDT)IBA
12/2023 - 01/2018
8selenomethylselenocysteine (methylselenocysteine)IBA
10/2018 - 07/2004
7SeleniumIBA
10/2018 - 04/2004
5Photosensitizing Agents (Photosensitizers)IBA
12/2023 - 01/2018
42-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a (HPPH)IBA
08/2022 - 01/2018
3Chlorophyll AIBA
04/2023 - 01/2022
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2012 - 12/2004
3Fluorouracil (Carac)FDA LinkGeneric
01/2005 - 02/2004
2Reactive Oxygen Species (Oxygen Radicals)IBA
06/2023 - 01/2010
2pyropheophorbide aIBA
08/2022 - 12/2020
2Erlotinib Hydrochloride (CP 358,774)FDA Link
01/2021 - 01/2019
2LipidsIBA
10/2018 - 10/2018
2Prolyl Hydroxylases (Prolyl Hydroxylase)IBA
10/2018 - 07/2012
2Proteins (Proteins, Gene)FDA Link
01/2010 - 02/2005
2Carbonic Anhydrase IXIBA
08/2008 - 12/2004
2Oxaliplatin (Eloxatin)FDA LinkGeneric
04/2006 - 01/2005
2raltitrexed (D 1694)IBA
04/2006 - 01/2005
1Bacteriochlorophyll AIBA
12/2023
1Retinaldehyde (Retinal)IBA
12/2023
1Oxygen (Dioxygen)IBA
06/2023
1Dihematoporphyrin Ether (Porfimer Sodium)FDA Link
06/2023
1Galectin 1 (LGALS1)IBA
06/2023
1Galectin 3 (LGALS3)IBA
06/2023
1EstersIBA
04/2023
1Carboxylic AcidsIBA
04/2023
1AcidsIBA
08/2022
1pheophorbide aIBA
08/2022
1CarbohydratesIBA
08/2022
1Galactose (Galactopyranose)FDA LinkGeneric
08/2022
1Doxorubicin (Adriamycin)FDA LinkGeneric
04/2022
11,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidIBA
01/2022
1polyacrylamideIBA
12/2020
1Singlet OxygenIBA
12/2020
1IonsIBA
12/2020
1Pentetic Acid (DTPA)FDA LinkGeneric
12/2020
1ErbB Receptors (EGF Receptor)IBA
01/2019
1Biomarkers (Surrogate Marker)IBA
10/2018
1Thymidine PhosphorylaseIBA
10/2018
1Drug CombinationsIBA
10/2018
1Methionine (L-Methionine)FDA Link
10/2018
1MicroRNAs (MicroRNA)IBA
10/2018
1Hypoxia-Inducible Factor 1IBA
07/2012
1Selenium CompoundsIBA
04/2012
1Topoisomerase I InhibitorsIBA
06/2011
1Angiogenesis InhibitorsIBA
06/2011
1Bevacizumab (Avastin)FDA Link
06/2011
1Small Interfering RNA (siRNA)IBA
10/2010
1methylselenic acidIBA
10/2010
1Antineoplastic Agents (Antineoplastics)IBA
01/2010
1Cystine (L-Cystine)IBA
01/2010
1Tirapazamine (SR 4233)IBA
08/2008
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
02/2007
1Celecoxib (Celebrex)FDA Link
02/2007
1DNA Repair EnzymesIBA
05/2005
1Fas Ligand Protein (Fas Ligand)IBA
05/2005
1Cytochrome P-450 CYP3AIBA
05/2005
16- (3- (2- hydroxyethyl)amino- 1- propyl)- 5,6- dihydro- 2,3- dimethoxy- 8,9- methylenedioxy- 5,11- dioxo- 11H- indeno(1,2- )isoquinolineIBA
02/2005
1Capecitabine (Xeloda)FDA Link
01/2005
1Differentiation AntigensIBA
12/2004
1involucrinIBA
12/2004
1pimonidazoleIBA
12/2004
1L-methionine gamma-lyaseIBA
07/2004
1Type I DNA Topoisomerases (Topoisomerase I)IBA
04/2004
1PoisonsIBA
04/2004

Therapy/Procedure

9Photochemotherapy (Photodynamic Therapy)
12/2023 - 01/2018
7Drug Therapy (Chemotherapy)
10/2018 - 12/2004
5Therapeutics
06/2023 - 12/2004
2Lasers (Laser)
01/2019 - 01/2018
1Induced Hyperthermia (Thermotherapy)
01/2018
1Radiotherapy
10/2010
1Combination Drug Therapy (Combination Chemotherapy)
12/2004